Programmable Biomaterials Laboratory
Can we use structural material properties on the nanoscale to engineer selective interactions at the bio-interface?
The goal of the Programmable Biomaterials Lab is to understand the molecular design rules behind selective multivalent interactions at the bio-interface. We use DNA as engineering tool to explore the importance of structural mechanics and precise control of valency and patterns on directional interactions and self-assembly.
Combining materials engineering with biophysics and molecular biology, we uniquely combine disciplines to unravel and translate the power of selective interactions in the low-valency regime.
Exploiting the multitude of structural properties presented by DNA, we create macromolecules that organize into functional materials to unravel the selective multivalent interplay with cellular interactions.
- DNA nanotechnology
- Supramolecular polymer self-assembly
- Soft matter
- Cell uptake and stability
- Immune engineering
Those who are inspired by a model other than Nature, a mistress above all masters, are laboring in vain.
Leonardo da Vinci
Check out the publication by Eva and Marianna here!